Familial cancer journal


Abstract Aim: to describe two cases of familial papillary thyroid carcinoma.

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Material and methods: patients were investigated by fine needle biopsy, MRI imaging and tumor biopsy, first case and histological examination of colonic and thyroid tumors first case and histological examination of familial cancer journal tumor second case. Results and discussion: case presentation: first case, 68 years old man had a colonic polyposis attenuated form with only a few polyps and a thyroid nodule. After hemicolectomy for a supposed colonic carcinoma with liver and lung metastases, histological examination revealed no malignant colonic disease.

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Two month later the diagnosis of invasive thyroid tumor with lymph node metastases was made, but only an open biopsy familial cancer journal done because tumor invasiveness demonstrated on MTI imaging. The biopsy identified presenza hpv papilloma virus papillary thyroid carcinoma.

Case 2: the son of the patient 30 years old without known diseases was invited to be assessed for thyroid disease.

Familial & Hereditary Colorectal Cancers

Ultrasound examination discovered a familial cancer journal nodule with microcalcifications. Microscopic examination done after total thyroidectomy revealed a cribriform morular variant of papillary thyroid carcinoma, a variant that is known to be associated with FAP. Radioiodine ablation was made followed by familial cancer journal thyroxine treatment.

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In the second case adenomatous polyposis was not found familial cancer journal. In our knowledge these are the first cases of familial thyroid papillary carcinomas in our setting.

Familial history allowed an earlier diagnosis and a good management of the disease in the second case. Conclusions: according to the literature and our first experience, screening for thyroid cancer must be done in all patients with FAP and in those with a FAP proband in the family.

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Макс связался с ним через маленьких роботов. Кстати, он-то и предложил устроить над тобой сток и тем сбил с толку полицию во время последнего обыска. Он все боялся, что тебя обнаружат. "И еще раз спасибо тебе, Ричард, - подумала Николь, пока Эпонина продолжала говорить. - Теперь я обязана тебе собственной жизнью по крайней мере трижды".

Endocr Pathol. Modern Pathology ; SS Cavaco BM. Endocrine-Related Cancer ; Richards ML. Thyroid ; Nilbert M, Kristoffersson U, Ericsson M, et al: Broad phenotypic spectrum in familial adenomatous polyposis; from early onset and severe familial cancer journal to familial cancer journal onset of attenuated polyposis with the first manifestation at age BMC Med Genet.

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Orphanet J Rare Dis ; 7. Histopathology ; Asian Familial cancer journal Surg.

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Clin Gastroenterol Hepatol. Clin Colorectal Cancer ; 11 4 : Head Neck ; Ann Surg.

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Articolele vă pot fi puse la dispoziţie la solicitare. Zancu, S. Bulai, I. Enea, V. Death anxiety and pain catastrophizing among male inmates with nonsuicidal self- injury behavior.

Lee S, Hong SW, Shin SJ,et al: Papillary thyroid carcinoma associated with familial adenomatous polyposis: molecular analysis of pathogenesis in a family and review of the literature. Endocr J. Am J Otolaryngol.

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Cetta F. Acta Cytol. Kurihara K, Shimizu S, Chong J, et al: Nuclear localization of immunoreactive beta-catenin is specific to familial adenomatous polyposis in papillary thyroid carcinoma.

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Jpn J Cancer Res. Ito Y, Miyauchi A, Ishikawa H, et al: Our experience of treatment of cribriform morular variant of papillary thyroid carcinoma; difference in clinicopathological features of FAP-associated and sporadic patients.

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Mc Donald TJ. Journal of Oncology.

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