Papillomaviruses, Human papillomavirus 52 positive squamous cell carcinoma of the conjunctiva


Department of Ophthalmology, Grigore T.

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E-mail: moc. We report the detection of HPV 52 in a sample papillomaviruses from a year-old patient with squamous cell carcinoma of the conjunctiva of the left eye.

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papillomaviruses The method used for the papillomaviruses of HPV was real time polymerase chain reaction. The evolution papillomaviruses favorable after surgical removal of the tumor and the patient was explained that long-term follow-up is essential to avoid recurrence. Keywords: Conjunctiva, eye, human papillomaviruses 52, real time polymerase chain reaction, squamous cell carcinoma Human papillomavirus HPV infection is strongly associated with anogenital tumors cervix, penis, vulva, vagina, anushead and neck cancers oral cavity, esophagus, larynxand nonmelanoma skin cancers squamous and basal cell carcinoma.

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papillomaviruses The association between HPV infection and eye tumors is little explored territory. Di Girolamo brings forward a two-hit theory papillomaviruses explains cancerogenesis in OSSN: The first hit is mediated by ultraviolet radiation exposure that causes genetic alteration and the second hit is mediated by HPV infection in the susceptible cells.

Case Report We present a unique papillomaviruses href="http://coroane-jerbe-funerare.ro/3862-detoxifierea-rinichilor.php">detoxifierea rinichilor of squamous cell carcinoma of papillomaviruses conjunctiva examined and treated in June The year-old patient presented at the Ophthalmology Department for mild stinging sensation and redness in the left eye for almost papillomaviruses and a half.

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Papillomaviruses has been treated for the last 2 months with dexamethasone eye drops for scleritis by papillomaviruses ophthalmologist.

The papillomaviruses admits being a heavy smoker for papillomaviruses 30 years and that in his free papillomaviruses he practices agriculture without using sunglasses.

All other ophthalmological findings were normal.

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Conjunctival culture was performed before surgery, and no bacterial infection was found. The CT scan papillomaviruses the papillomaviruses and neck papillomaviruses no signs of tumor invasion of the orbit or the lymph nodes.

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The limbic lesion was removed papillomaviruses with 2 mm margin of papillomaviruses tissue and diathermy of the adjacent sclera papillomaviruses done. At the end, the remaining temporal defect was restored using a supero-nasal conjunctiva graft fixed in position papillomaviruses interrupted and surjet The excised tumor was cut into 2 fragments: One for pathology preserved in formalin and papillomaviruses for HPV genotyping preserved in Cobas polymerase chain reaction PCR solution and refrigerated at 4°C until papillomaviruses.

Histopathology exam showed a moderate differentiated keratinized squamous cell carcinoma of the conjunctiva without koilocytosis [Figs.

This is one of papillomaviruses most common sexually transmitted infections, with a tropism for tissues such papillomaviruses squamous or mucosal epithelium. Human papillomavirus can be classified papillomaviruses to the ability of oncogenesis in low-risk genotypes, associated primarily with genital warts and high-risk, associated with premalignant and malignant lesions.