Congenital squamous papillomas. Programe analitice


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Out of all the prezentau pe suprafaþa NSJ formaþiuni tumorale, o patients, 7 patients 5. NSJ se face la o vârstã adultã. Aceste neoplazii epiteliale Studies have shown that malignancies on NSJ occur at sunt de obicei benigne, cele mai des întâlnite fiind siringo- an adult age. These are usually benign epithelial cancers, cistadenomul papilifer, trichoblastomul ºi tricholeio- the most common being the syringocystadenoma papilli- miomul.

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Neoplaziile epiteliale maligne apãrute pe NSJ sunt ferum, trichoblastoma and tricholeiomyoma. Malignant rar întâlnite mai frecvent fiind carcinomul bazocelular.

Cuvinte cheie: nev sebaceu Jadassohn, tricoblastom, siringocistadenom papilifer, carcinoma bazocelular. Key words: nevus sebaceous of Jadassohn, trichobla- stoma, syringocystadenoma papilliferum, basal cell carcinoma. Intrat în redacþie: Nevul sebaceu change [2]. Nevus sebaceous of Jadassohn NSJ Jadassohn NSJ este prezent de la naºtere sub is present at birth as a usually unique plate, forma unei plãci de obicei unice, circumscrise, de circumscribed, yellow or yellow-brown in color, coloraþie galbenã sau galben-brun, lipsitã de pãr, hairless, round, semilunar or linear in shape, at de formã rotundã, semilunarã sau liniarã, la puberty the surface of the lesion becoming pubertate suprafaþa leziunii devenind granularã granular or verrucous.

NSJ is located most sau verucoasã. NSJ este localizat cel mai frecvent commonly congenital squamous papillomas the scalp Mehregan ºi Pinkus [4] considerã cã existã Mehregan and Pinkus [4] believe that there trei stadii evolutive. Primul stadiu aparþine are three stages of evolution.

The first stage copilãriei ºi se caracterizeazã congenital squamous papillomas subdezvoltarea belongs to childhood and is characterized by structurilor anexiale. Stadiul al doilea este cel al underdevelopment of the adnexal structures. The pubertãþii ºi are ca ºi caracteristicã dezvoltarea second stage is that congenital squamous papillomas puberty and its masivã a glandelor sebacee, hiperplazia characteristic is the massive development of verucoasã epidermalã ºi maturarea glandelor sebaceous glands, congenital squamous papillomas verrucous hyper- apocrine.

Specificații

Ultimul stadiu este cel post-pubertal plasia and maturation of apocrine glands. Last caracterizat prin what is hpv papilloma apariþiei neo- stage is post-pubertal and is characterized by the plaziilor benigne ºi mai rar al celor maligne.

Tricoblastomul ºi adnexal or mesenchymal nature [5][6][7][8]. Material ºi metodã Material and method Prezentãm un studiu clinico-patologic inclu- zând congenital squamous papillomas de nev sebaceu Jadassohn We present a congenital squamous papillomas study othat diagnosticate pe o perioadã de 15 ani în cadrul includes cases of SNJ diagnosed over a period cabinetului S.

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Dermamed Braºov. The clinical data vârsta, sexul ºi localizarea anatomicã, iar exa- congenital squamous papillomas obtained from each patient including age, minarea histopatologicã a fost efectuatã din gender, anatomic location and histopathological fiecare tumorã dezvoltatã pe NSJ. Statistical programului Microsoft Excel.

Jadassohn were evaluated for this study. Out of the patients, 7 patients 5. Histopathological examination of evidenþiat 7 tricoblastoame fig. Astfel, cea mai patient fig. Thus, the most common frecventã neoplazie gãsitã a fost tricoblastomul, malignancy was trichoblastoma followed by urmatã de siringocistadenom papilifer. Aspect clinic al nevului congenital squamous papillomas Clinical Congenital squamous papillomas. Aspect clinic a 4 tricoblastoame dezvoltate pe acelaºi Fig.

Aspect clinic al siringocistadenomului papilifer Fig. Aspect clinic al carcinomului bazo-celular dezvoltat Fig. Aspect histopatologic al carcinomului bazo-celular pe NSJ Clinical appearance of basal cell carcinoma dezvoltat pe NSJ Histopathological appearance of basal cell developed on NSJ carcinoma developed on NSJ Discuþii Discussions Tumorile care se dezvoltã pe NSJ apar de Tumors that develop on NSJ usually occur in obicei la vârsta adultã prezentându-se ca noduli adults presenting as solitary or multiple nodules solitari sau multipli al cãror aspect clinic poate fi of which papiloma humano vacuna edad may be clinically confused with confundat cu diferite tumori inclusiv mela- different tumors including melanoma.

The most nomul.

Cele mai frecvente tumori apãrute pe NSJ common tumors occurring on NSJ are syringo- sunt siringocistadenomul papilifer ºi trico- cystadenoma papilliferum and trichoblastoma.

Majoritatea autorilor [4], [9], [10] au Most authors [4], [9], [10] found syringocyst- gãsit siringocistadenomul papilifer ca cea mai adenoma papilliferum as the most frequent frecventã tumorã apãrutã pe NSJ, deosebindu-se tumor appeared on NSJ, unlike the Chun et al. Tricoblastomul este o tumorã contro- Trichoblastoma is a controversial tumor, many versatã, multe cazuri congenital squamous papillomas anterior ca fiind cases previously considered to be basal cell carcinoame bazocelulare erau în realitate trico- carcinomas were in fact trichoblastomas.

Trichilemoamele pot fi interpretate ca Trichilemmoma can be interpreted as endophytic papiloame endofitice având celule clare cu papillomas with clear cells highlighting HPV evidenþierea HPV [12], pe nevul sebaceu putând [12], on the nevus sebaceous can be also found fi gãsite de altfel ºi papiloame virale adevãrate.

Jaqueti et al [3]on a clinico- efectuat pe NSJ de la pacienþi nu pathological study conducted on patients menþioneazã gãsirea vreunei leziuni maligne with NSJ do not mention finding any motiv pentru care considerã ca nefiind necesarã malignant lesions and for that reason consider excizia timpurie a NSJ în scopul prevenirii the early excision to be unnecessary in congenital squamous papillomas to apariþiei tumorilor maligne pe suprafaþa acestuia.

Chun et al. Cribier ºi colab [5] syringocystadenoma papilliferum and tricho- examinând NSJ de la pacienþi congenital squamous papillomas toate blastoma. Santibanez-Gallerani ºi colab. Santibanez-Gallerani et al. Kazakov ºi colab.

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Kazakov et al. There is the possi- tumori diferite pe acelaºi NSJ ca de exemplu bility of the presence of two or three different asocierea siringocistadenomului papilifer cu tumor on the same NSJ like syringo-cystadenoma tricoblastomul.

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Dupã cum se poate observa, studiile As can congenital squamous papillomas seen, the studies presented congenital squamous papillomas prezentate au arãtat cã incidenþa tumorilor that the incidence of benign or malignant tumors benigne sau maligne apãrute la copil pe NSJ este congenital squamous papillomas from NSJ in children is low. Thus Cribier scãzutã. Astfel Cribier ºi colab. Concluzii Conclusions Faptul cã congenital squamous papillomas mare de studii efectuate The fact that congenital squamous papillomas large number of studies have au arãtat cã majoritatea NSJ nu prezintã asocieri shown that most NSJ do not present any cu tumori maligne, iar acestea apar doar la vârste association with malignant tumors and they adulte aduce în discuþie urmãrirea clinicã a appear only in adulthood brings into question acestor leziuni congenital squamous papillomas alternativã la excizia chirur- the clinical follow up of these lesions as an gicalã timpurie a NSJ.

Programe analitice - Anatomie patologica - UMF "Carol Davila"

Jadassohn J. Arch Dermatol Syphilol.

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Nevus sebaceous revisited. Pediatr Dermatol ; Trichoblastoma is the congenital squamous papillomas common neoplasm developed in nevus sebaceus of Hadassohn: a clinicopathology study of a series of cases. Am J Dermatopathol. Mehregan AH, Pinkus H. Life history of organoid nevi. Special reference to nevus sebaceus of Jadassohn. Arch Dermatol. Tumors arising in nevus sebaceus: a study of cases. J Am Acad Dermatol.

Secondary neoplasms associated with nevus sebaceous of Jadassohn: a study of cases. J Am Acad Dermatol ; Management of nevus sebaceous and the risk of Basall cell carcinoma: an year review.

Sebaceus naevi: a clinicopathological study.

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J Eur Acad Dermatol Venereol ; Wilson Jones E, Heyl T. Br J Dermatol. Ann Dermatol Venereol.

Nevus sebaceous: clinical outcome and considerations for prophylactic excision. Int J Dermatol. Steffen C, Ackerman AB — neoplasms with sebaceous differentiation. Domingo J, Helwig EB. Malignant neoplasms associated with nevus sebaceus of Jadasohn.

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Should nevus sebaceus of Jadassohn in children be excised? A study of cases, and literature review. J Craniofac Surg. Sebaceous carcinoma arising in nevus sebaceus of Jadassohn: a clinicopathological study of five cases.

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