The incidence of GEP-NENs has increased worldwide neuroendocrine cancer organizations the past decades, with the small intestine, rectum, and pancreas as the most common tumor locations.
Lung Neuroendocrine Tumors: Imaging and Diagnosis with Robert Ramirez, OD
The epidemiological characteristics, pathogenesis and treatment have raised many questions, and some of them are still being debated. Here, we report a case of gastric collision tumor with large-cell neuroendocrine carcinoma and adenocarcinoma.
A year-old male patient with a history of gastric resection performed 30 years ago, with no medical records revealing the type of resection or the reconstructive way, presented with epigastric pain. The endoscopy revealed a solid, ulcerated mass at the gastrojejunal anastomosis site from which a tissue neuroendocrine cancer organizations was taken, which was neuroendocrine cancer organizations as adenocarcinoma.
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For staging, the patient underwent an abdominal CT scan, which showed the thickening of the gastric wall adjacent to anastomosis and perilesional adenopathy. The patient underwent a subtotal gastrectomy and regional lymphadenectomy.
MATERIALS Neuroendocrine cancer organizations METHODS: Imaging studies of 22 patients 12 men, mean age 60 years with histopathologically confirmed diagnosis, evaluated in the authors's institution during the last five years were retrospectively reviewed by two radiologists, with findings being consensually described focusing on changes observed at computed tomography.
A diagnosis of large-cell neuroendocrine carcinoma developed on the gastric stump associated with isolated foci of moderately differentiated tubular adenocarcinoma pT3N1G3 was made. Immunohistochemical analysis is essential for the diagnosis and classification of the lesion. To confirm the diagnosis, Chromogranin A and Synaptophysin are needed, and for prognostic evaluation the identification of Ki and mitotic figure count are required.
Controversies in the treatment of digestive neuroendocrine tumors. J Cancer Metasta Treat ; Neuroendocrine neuroendocrine cancer organizations of the gastrointestinal tract.
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